The presentation will address the critical need for safer training methods in preparing canines for the detection of fentanyl, a potent synthetic opioid. Traditional canine training for drug detection often involves using actual substances (bulk drugs) like fentanyl, which poses significant health risks to both the dogs and their handlers. To mitigate these risks, researchers and commercial entities have actively been exploring alternative training aids that can mimic the odor of fentanyl without the associated dangers. Considerations, including odor profiles, stability and degradation, and training aids related to canine detection of drugs including fentanyl-related opioids will be discussed. Finally, training aid selection, storage and handling will also be covered.